CAS 1414-45-5 E234 Nisin Natural Antimicrobial Peptide Powder

CAS 1414-45-5 E234 Nisin Natural Antimicrobial Peptide

Nisin (E234) is a natural antimicrobial peptide produced by the bacterium Lactococcus lactis. It is used as a food preservative to inhibit the growth of bacteria, particularly those responsible for food spoilage and foodborne illnesses.

Description:
Nisin is a polycyclic antibacterial peptide consisting of 34 amino acid residues. It is a naturally occurring compound produced by fermentation using the bacterium Lactococcus lactis. Nisin has a broad spectrum of antimicrobial activity, primarily targeting Gram-positive bacteria, including certain strains of Listeria, Staphylococcus, Clostridium, and Bacillus.

Data Sheet:

• Chemical Name: Nisin
• E Number: E234
• Molecular Formula: C₁₂₉H₂₁₀N₃₉O₃₇S₇
• Molecular Weight: Approximately 3,500 g/mol
• Appearance: White to pale yellow powder
• Solubility: Soluble in water and some organic solvents
• Stability: Stable under normal storage conditions

SPECIFICATION:

Features:

1. Antimicrobial Activity: Nisin exhibits potent antimicrobial activity against a broad range of Gram-positive bacteria, including some antibiotic-resistant strains. It disrupts the bacterial cell membrane, leading to cell death.
2. Heat Stability: Nisin retains its antimicrobial activity even after exposure to high temperatures, making it suitable for use in heat-treated food and beverage products.
3. pH Stability: Nisin remains active over a wide range of pH levels, including acidic conditions, which allows for its use in various food formulations with different pH requirements.
4. Natural Origin: Nisin is produced naturally by the bacterium Lactococcus lactis, making it a natural food preservative. It is generally recognized as safe (GRAS) by regulatory authorities.
5. Synergistic Effects: Nisin can exhibit synergistic effects with other preservatives, such as organic acids, enhancing the overall antimicrobial activity and reducing the required concentrations of each component.

Applications:

1. Food Preservation: Nisin is primarily used as a food preservative to prevent spoilage caused by bacteria. It is commonly incorporated into a variety of food and beverage products, including dairy products (cheese, yogurt), processed meats, canned foods, sauces, dressings, and baked goods.
2. Beverage Industry: Nisin is used to inhibit spoilage bacteria and extend the shelf life of beverages, such as fruit juices, soft drinks, and alcoholic beverages.
3. Meat and Poultry Processing: Nisin is utilized in meat and poultry processing to control the growth of harmful bacteria, such as Listeria monocytogenes and Clostridium botulinum, thereby enhancing food safety.
4. Chemical Industry: Nisin finds applications in the Chemical industry as a preservative in certain oral healthcare products, throat lozenges, and topical formulations.
5. Animal Feed: Nisin is sometimes added to animal feed to inhibit the growth of bacteria and improve the shelf life and safety of the feed.