CAS 7681-93-8 Antifungal Compound Pimaricin E235 Natamycin White Powder

Natamycin is a naturally occurring antifungal compound that is widely used as a food preservative. It is derived from the fermentation of the bacterium Streptomyces natalensis and is effective against a broad spectrum of molds and yeasts.

Description:
Natamycin, also known as pimaricin or E235, is a polyene macrolide compound with the chemical formula C₃₃H₄₇NO₁₄. It is a white to yellowish powder with low solubility in water and is stable at a wide range of temperatures and pH levels. Natamycin is odorless and tasteless.

Data Sheet:

• Chemical Name: Natamycin
• Chemical Formula: C₃₃H₄₇NO₁₄
• Molecular Weight: 665.73 g/mol
• Appearance: White to yellowish powder
• Solubility: Insoluble in water; soluble in organic solvents (e.g., ethanol)
• Melting Point: Approximately 280 °C (536 °F)

Features:

1. Antifungal Properties: Natamycin is primarily known for its potent antifungal properties. It effectively inhibits the growth and reproduction of various molds and yeasts, including Aspergillus, Penicillium, and Candida species.
2. Wide Spectrum of Activity: Natamycin displays a broad spectrum of activity against molds and yeasts commonly found in food and beverages. It provides effective control of fungal spoilage, helping to extend the shelf life of products.
3. Heat Stability: Natamycin maintains its antifungal activity even at elevated temperatures, making it suitable for use in heat-processed food products.
4. pH Stability: Natamycin remains effective over a wide range of pH levels, including both acidic and alkaline conditions, which allows for its use in various food and beverage applications.
5. Low Toxicity: Natamycin is considered safe for consumption when used within recommended limits. It has low toxicity and does not accumulate in the body.

Applications:

1. Food Preservation: Natamycin is extensively used as a preservative in the food and beverage industry. It helps prevent fungal spoilage in a wide range of products, including dairy products (e.g., cheese, yogurt), baked goods, meat and poultry, beverages (e.g., fruit juices, wines), and processed foods.
2. Agricultural Applications: Natamycin is sometimes used in agriculture to prevent fungal infections in crops, such as fruits and vegetables, by applying it as a protective coating or dip.
3. Chemical Applications: Natamycin has limited applications in the Chemical industry. It is used in some ophthalmic formulations, such as eye drops and ointments, to treat fungal eye infections.
4. Animal Feed: Natamycin is occasionally added to animal feed to prevent fungal growth and safeguard the quality and safety of the feed.
5. Cosmetic and Personal Care Products: Natamycin is used as a preservative in certain cosmetic and personal care products, including creams, lotions, and ointments, to prevent microbial contamination.

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