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Acitretin 99% Purity CAS 55079-83-9 for Psoriasis Treatment

Name: Acitretin 99% Purity CAS 55079-83-9 for Psoriasis Treatment
Brand: Shanxi Zorui Biotechnology Co., Ltd.
SKU: 55079-83-9
Availability: InStock

Brand Name:	Zorui
Model Number:	55079-83-9
MOQ:	25 KG
Payment Terms:	L/C,D/A,D/P,T/T

Detail Information

Product Description

Detail Information

Place of Origin:

China

Certification:

ISO

ProName:

Acitretin

CAS No.:

55079-83-9

Molecular Formula:

C21H26O3

EINECS:

259-474-4

Appearance:

Yellow Crystalline Powder

Delivery Time:

Within 3 Working Days

Package:

25KG/Drum, As Customers Request

Port:

Tianjin, Shanghai, Qingdao, Ningbo

Production Capacity:

3000 Metric Ton/Month

Purity:

≥99%

Storage:

Cool Dry Place

Transportation:

By Sea Or By Air

Shelf Life:

2 Years

Packaging Details:

25KG/Drum, as customers request

Highlight:

Acitretin 99% purity psoriasis treatment

Acitretin CAS 55079-83-9 chemical raw

High purity Acitretin for psoriasis

Product Description

CAS 55079-83-9 Acitretin For Treatment Of Psoriasis Scaling And Inflammation

Product Description

Description

Acitretin is a second-generation retinoid used primarily for the treatment of severe psoriasis and other keratinization disorders. It is the active metabolite of etretinate, with a shorter half-life but similar efficacy. Acitretin works by modulating keratinocyte proliferation and differentiation, reducing scaling and inflammation.

Technical Data Table

Property	Value / Specification
Chemical Name	Acitretin (all-trans-9-(4-methox-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic acid)
CAS No.	55079-83-9
Molecular Formula	C₂₁H₂₆O₃
Molecular Weight	326.43 g/mol
Appearance	Yellow crystalline powder
Melting Point	~220–225 °C (decomposes)
Solubility	Insoluble in water; soluble in ethanol, DMSO
LogP (Octanol-Water)	~6.2 (highly lipophilic)
Half-Life	~50 hours (active metabolite: ~60 days)
Storage Conditions	2–8 °C (protect from light & moisture)

Key Features

✅ Potent Retinoid Activity – Normalizes keratinocyte differentiation.
✅ Oral Bioavailability – Well-absorbed (~60–80%) with fatty meals.
✅ Long-Term Efficacy – Sustained improvement in plaque psoriasis.
✅ Teratogenic Risk – Pregnancy Category X (strict contraception required).
✅ Synergistic with UV Therapy – Enhances PUVA/UVB treatment effects.

Applications (Medical Uses)

Plaque Psoriasis – First-line systemic therapy for severe cases.
Pustular Psoriasis – Effective for palmoplantar and generalized forms.
Darier’s Disease – Reduces hyperkeratosis and lesions.
Lichen Planus – Off-label use for severe cutaneous variants.
Cutaneous T-cell Lymphoma (CTCL) – Adjunct therapy in early stages.

Dosage & Administration

Initial Dose: 25–50 mg/day (adjust based on response/tolerance).
Maintenance Dose: 10–50 mg/day (long-term use possible).
Administration: Taken with food (fat enhances absorption).

Side Effects & Warnings

⚠ Common: Dry skin/mucous membranes, alopecia, hyperlipidemia.
⚠ Serious: Hepatotoxicity, teratogenicity, osteoporosis (long-term).
⚠ Contraindications: Pregnancy, breastfeeding, severe liver/kidney disease.

Comparison with Other Retinoids

Retinoid	Half-Life	Teratogenicity	Primary Use
Acitretin	~50 hours	High (Category X)	Psoriasis, keratinization disorders
Isotretinoin	~20 hours	High (Category X)	Severe acne
Tretinoin (Topical)	N/A	Low	Acne, photoaging
Etretinate (Discontinued)	120 days	Extreme	Historical psoriasis treatment

Packaging & Shipping

Packaging	1kg-15kg packing	2 PE bag inside + 1 foil bag outside in carton
	25kg-50kg packing	2 PE bag inside + 1 foil bag outside in drum
	Other packing	Customized packing
Drum Size	D38cm*H60cm or customized, 25 kg/ drum
Shipping	1-50kg	International Express	Fast and convenient	Door to Door
	50-500kg	Air Transportation	Fast and cheap	To Air Port
	Above 500kg	Sea Transportation	Cheap and convenient	To Port

Loading & Transport

Transportation	Mode of Transport	Brand	Shipping Time	Start and Destination	Style
Express	DHL		3-6 Days	Door to Door	Sample
	FEDEX		3-6 Days	Door to Door	Sample
	UPS		3-6 Days	Door to Door	Sample
	TNT		3-6 Days	Door to Door	Sample
	EMS		8-15 Days	Door to Door	Sample
Air	By Plane		3-7 Days	Airport to Airport	Order
Sea	By Ship		Asia: 15-20 Days Europe: 25-35 Days America: 30-40 Days	Port to Port	Order

FAQ

Q1: How to contact with us?

Whatsapp us or send us e-mail, you will get reply within 24 hours. Please contact us without hesitation.

Q2: Which kind of payment terms do you accept?

We support multiple trading methods and payment such as T/T, L/C, D/A, D/P, O/A, MoneyGram, Credit Card, PayPal, Western Union, Escrow and etc. Please contact us if you need more info.

Q3: How can i get a sample?

Yes, you can get free samples for some products, but the shipping cost would be paid by customers.

Q4: How to confirm the Product Quality before placing orders

You can get some sample, or we can send certificate of analysis or HPLC or NMR to you.

Q5: How to guarantee the quality of your products?

Strict sampling inspection on products before shipment and intact product packaging ensured.

Q6: How can I make payment safe?

The whole transaction is under Third party inspection.

Q7: Whether you could make our brand on your products?

Yes. We can print your Logo on the packages if you can meet our MOQ.

Why Choose Us

1.Best quality with competitive price.

2.Quick shipping,delivery on time.

3.Trade Assurances

4. Support multiple trading methods and payment. We support wire transfer, western union, Paypal payment.

5.One to one business communication

6.OEM/ODM Available.

7.We offer convenient one-station purchasing service.Our professional and thoughtful after-sales service eliminates your worries.

8. We has many years’ exporting experience in active Chemical ingredient products, strictly on selecting raw materials

9.Our distribution capabilities include:

Flexible deliveries, intelligent solutions

Anything from bulk shipments of thousands of tonnes down to the smallest shipment of packed goods and even samples.

Bulk - storage and transport of powders and liquids – movement of goods in ships - powders and bulk liquids

Chemical, feed and food storage to accredited standards

Segregated materials by business unit and hazard classification

Temperature controlled storage and transport

Effective cost control

Re-packing, drum filling, bagging

Customer delivery KPI's on delivery fulfillment performance

Tags:

Food And Feed Additives

Industrial Grade Chemicals

EDTA 4Na

Amino Acid Powder

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Vitamin Fine Powder

Granular Activated Carbon

Natural Food Sweeteners

Water Treatment Chemicals

EVOH Resin

Plant Extract Powder

Carboxymethyl Cellulose CMC

Diammonium Phosphate Fertilizer

Chemical Raw Materials

Food And Feed Additives

Industrial Grade Chemicals

EDTA 4Na

Amino Acid Powder

Cosmetic Raw Materials

Vitamin Fine Powder

Granular Activated Carbon

Natural Food Sweeteners

Water Treatment Chemicals

EVOH Resin

Plant Extract Powder

Carboxymethyl Cellulose CMC

Diammonium Phosphate Fertilizer

Chemical Raw Materials

products details

Acitretin 99% Purity CAS 55079-83-9 for Psoriasis Treatment

Acitretin 99% Purity CAS 55079-83-9 for Psoriasis Treatment

Acitretin 99% purity psoriasis treatment

Acitretin CAS 55079-83-9 chemical raw

High purity Acitretin for psoriasis

Description

Technical Data Table

Key Features

Applications (Medical Uses)

Dosage & Administration

Side Effects & Warnings

Comparison with Other Retinoids